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Figure 3
RAD001 treatment leads to MAPK activation in Pten-null prostate conditional mice. (A) p-ERK immunostaining in Pten-null mouse prostates treated with vehicle or RAD001 for 4 weeks. A representative area is shown. n = 3 mice per group. (B) Quantification of p-ERK staining in hot spots (high–p-ERK areas). **P < 0.01 compared with vehicle treatment. Error bars indicate SD.