MALDI Imaging mass spectrometry has entered the field of tissue-based research by
providing unique advantages for analyzing tissue specimen in an unprecedented detail. A
broad spectrum of analytes ranging from proteins, peptides, protein modification over small
molecules, drugs and their metabolites as well as pharmaceutical components, endogenous
cell metabolites, lipids, and other analytes are made accessible by this in situ technique in
tissue. Some of them were even not accessible in tissues within the histological context …