Three-dimensional reconstruction of hepatic bridging fibrosis in chronic hepatitis C viral infection

A Hoofring, J Boitnott, M Torbenson - Journal of hepatology, 2003 - Elsevier
Background/Aims: Fibrosis in chronic hepatitis C infection begins in portal tracts, and can
progress to 'bridging fibrosis' and eventually lead to cirrhosis. All current fibrosis staging
systems are based on these three conceptual fibrosis stages (portal fibrosis, bridging
fibrosis, cirrhosis) and vary only in how these stages are further subdivided. Despite the
importance of bridging fibrosis, little is known about its three-dimensional characteristics.
Methods: Foci of bridging fibrosis were digitally reconstructed in three dimensions on two …