Expression of the novel extracellular matrix component tenascin in normal and diseased human liver: an immunohistochemical study
P Van Eyken, R Sciot, VJ Desmet - Journal of hepatology, 1990 - Elsevier
The novel extracellular matrix glycoprotein tenascin was studied immunohistochemically in
normal and fibrotic human liver. Its localization was compared to that of laminin, fibronectin
and collagen type IV. In the normal liver, a weak staining for tenascin was detected along
sinusoids, while portal tracts were negative. In both alcoholic and cholestatic liver disease
and acute and chronic hepatitis, sinusoidal immunoreactivity for tenascin was variably
increased as compared to the normal liver. Most striking, however, was the preferential …
normal and fibrotic human liver. Its localization was compared to that of laminin, fibronectin
and collagen type IV. In the normal liver, a weak staining for tenascin was detected along
sinusoids, while portal tracts were negative. In both alcoholic and cholestatic liver disease
and acute and chronic hepatitis, sinusoidal immunoreactivity for tenascin was variably
increased as compared to the normal liver. Most striking, however, was the preferential …