[HTML][HTML] Genetics of liver disease: from pathophysiology to clinical practice
TH Karlsen, F Lammert, RJ Thompson - Journal of Hepatology, 2015 - Elsevier
Paralleling the first 30 years of the Journal of Hepatology we have witnessed huge
advances in our understanding of liver disease and physiology. Genetic advances have
played no small part in that. Initial studies in the 1970s and 1980s identified the strong major
histocompatibility complex associations in autoimmune liver diseases. During the 1990s,
developments in genomic technologies drove the identification of genes responsible for
Mendelian liver diseases. Over the last decade, genome-wide association studies have …
advances in our understanding of liver disease and physiology. Genetic advances have
played no small part in that. Initial studies in the 1970s and 1980s identified the strong major
histocompatibility complex associations in autoimmune liver diseases. During the 1990s,
developments in genomic technologies drove the identification of genes responsible for
Mendelian liver diseases. Over the last decade, genome-wide association studies have …