Collagen synthesis by human liver (myo) fibroblasts in culture: evidence fora regulatory role of IL-1β, IL-4, TGFβ and IFN gamma
AMBC Tiggelman, W Boers, C Linthorst, M Sala… - Journal of …, 1995 - Elsevier
BACKGROUND/AIMS:: Different cytokines have been described in fibrotic livers, including
interleukin-1, interleukin-4 and interferon gamma, which are capable of regulating collagen
production in human skin and lung fibroblasts METHODS:: To investigate possible
involvement of interleukin-1, interleukin-4 and interferon gamma in the regulation of
collagen production in human liver fibrosis, we studied the effects of these cytokines on
collagen synthesis by nonparenchymal human liver cells in vitro. The effects of interleukin-1 …
interleukin-1, interleukin-4 and interferon gamma, which are capable of regulating collagen
production in human skin and lung fibroblasts METHODS:: To investigate possible
involvement of interleukin-1, interleukin-4 and interferon gamma in the regulation of
collagen production in human liver fibrosis, we studied the effects of these cytokines on
collagen synthesis by nonparenchymal human liver cells in vitro. The effects of interleukin-1 …
