[HTML][HTML] Reversibility of fibrosis, inflammation, and endoplasmic reticulum stress in the liver of rats fed a methionine–choline-deficient diet
Y Mu, T Ogawa, N Kawada - Laboratory investigation, 2010 - Elsevier
Fatty liver disease has become a health problem related to metabolic syndrome worldwide,
although its molecular pathogenesis requires further study. It is also unclear whether
advanced fibrosis of steatohepatitis will regress when diet is controlled. The aim of this study
was to investigate whether the resolution of fibrosis occurs in steatohepatitis induced by a
methionine–choline-deficient diet (MCDD). Manifestation of endoplasmic reticulum (ER)
stress in this model was also studied. Nonalcoholic steatohepatitis with advanced fibrosis …
although its molecular pathogenesis requires further study. It is also unclear whether
advanced fibrosis of steatohepatitis will regress when diet is controlled. The aim of this study
was to investigate whether the resolution of fibrosis occurs in steatohepatitis induced by a
methionine–choline-deficient diet (MCDD). Manifestation of endoplasmic reticulum (ER)
stress in this model was also studied. Nonalcoholic steatohepatitis with advanced fibrosis …
