Changes in portal circulation after biliary obstruction in dogs

EG Ohlsson, RB Rutherford, JK Boitnott… - The American Journal of …, 1970 - Elsevier
Eighteen mongrel dogs were studied before and at three and four week intervals after
common bile duct ligation in regard to changes in results of hepatic function tests and
histology, portal pressures, and the degree of portasystemic shunting of differently labelled
15±5 and 25±5 μ particles injected into the portal vein. The demonstration of sinusoidal
dilatation and increased intrahepatic portasystemic shunting at the 15 μ level in the majority
of dogs by the fourth week of biliary obstruction, and its correlation with changes in portal …