Changes in WNT/β-catenin pathway during regulated growth in rat liver regeneration
SPS Monga, P Pediaditakis, K Mule, DB Stolz… - Hepatology, 2001 - Elsevier
The wnt/β-catenin pathway is important during embryogenesis and carcinogenesis. β-
Catenin interaction with E-cadherin has been shown to be crucial in cell-cell adhesion. We
report novel findings in the wnt pathway during rat liver regeneration after 70% partial
hepatectomy using Western blot analyses, immunoprecipitation studies, and
immunofluorescence. We found wnt-1 and β-catenin proteins to be predominantly localized
in hepatocytes. Immediately following partial hepatectomy, we observed an initial increase …
Catenin interaction with E-cadherin has been shown to be crucial in cell-cell adhesion. We
report novel findings in the wnt pathway during rat liver regeneration after 70% partial
hepatectomy using Western blot analyses, immunoprecipitation studies, and
immunofluorescence. We found wnt-1 and β-catenin proteins to be predominantly localized
in hepatocytes. Immediately following partial hepatectomy, we observed an initial increase …