Comparative observation of fibroblasts derived from the papillary and reticular dermis of infants and adults: growth kinetics, packing density at confluence and surface …

IA Schafer, M Pandy, R Ferguson, BR Davis - Mechanisms of ageing and …, 1985 - Elsevier
We have confirmed the reports of Harper and Grove (Science, 204 (1979) 526–527), and
Azzarone and Macierira-Coehlo (J. Cell Sci. 57 (1982) 177–187) that fibroblasts derived
from the papillary dermis have greater in vitro growth potential and longer replicative
lifespans than genomically identical fibroblasts derived from the reticular dermis. In addition
we demonstrate that the kinetics of cell replication differ for papillary and reticular fibroblasts
derived from infant and adult donors. Infant papillary fibroblasts replicate at faster rates than …