Kinetic analysis using specific radioactivity data

NA Le, R Ramakrishnan, RB Dell, HN Ginsberg… - Methods in …, 1986 - Elsevier
Publisher Summary This chapter focuses on the kinetic analysis using specific radioactivity
data. In kinetic turnover studies, a tracer amount of radiolabeled material is injected
intravenously as a bolus. The biologic half-life and/or the in vivo metabolic fate of the
material of interest can then be determined by analyzing the decay curve, which describes
the disappearance of the injected. Available programs for compartmental analysis, however,
are primarily designed for the analysis of total radioactivity (TR) data. Thus even if specific …