[HTML][HTML] Molecular cloning and characterization of another leukotriene B4 receptor
M Kamohara, J Takasaki, M Matsumoto, T Saito… - Journal of Biological …, 2000 - ASBMB
Leukotriene B 4 is a potent lipid mediator known to be implicated mainly in inflammatory
actions. Previous pharmacological studies indicated the existence of only one class of G
protein-coupled receptor for leukotriene B 4, for which a candidate gene, namely BLT, had
been identified. Here we report the isolation of another gene encoding a functional G protein-
coupled receptor for leukotriene B 4, named JULF2. JULF2 is a novel G protein-coupled
receptor of 358 amino acids that shares 36.6% amino acid identity with human BLT …
actions. Previous pharmacological studies indicated the existence of only one class of G
protein-coupled receptor for leukotriene B 4, for which a candidate gene, namely BLT, had
been identified. Here we report the isolation of another gene encoding a functional G protein-
coupled receptor for leukotriene B 4, named JULF2. JULF2 is a novel G protein-coupled
receptor of 358 amino acids that shares 36.6% amino acid identity with human BLT …
