Experimental study of physical factors, including fibrin formation, influencing the spread of fluids and small particles within and from the peritoneal cavity of the dog

HH Zinsser, AW Pryde - Annals of Surgery, 1952 - journals.lww.com
HH Zinsser, AW Pryde
Annals of Surgery, 1952journals.lww.com
Steinbergº 9**** has maintained that the spread of infection in the peritoneal cavity from a
focus such as a ruptured vis-cus is exceedingly rapid and that it is virtually complete within
three hours. This is not im accord with the view of many clinicians, that the process may be
slow enough in some instances to permit limitation of the infection by the local formation of
fibroplastic exudate. That the extent and rapidity of spread may be subject to a num-ber of
variables, specifically the nature of the exudate, and the condition of the peritoneum …
Steinbergº 9**** has maintained that the spread of infection in the peritoneal cavity from a focus such as a ruptured vis-cus is exceedingly rapid and that it is virtually complete within three hours. This is not im accord with the view of many clinicians, that the process may be slow enough in some instances to permit limitation of the infection by the local formation of fibroplastic exudate. That the extent and rapidity of spread may be subject to a num-ber of variables, specifically the nature of the exudate, and the condition of the peritoneum, seemed possible, and to test this a variety of radiopaque liquid mixtures were introduced into the peritoneal cavity.
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