Effects of n-3 FA supplementation on the release of proresolving lipid mediators by blood mononuclear cells: the OmegAD study [S]
X Wang, E Hjorth, I Vedin, M Eriksdotter… - Journal of lipid …, 2015 - ASBMB
Specialized proresolving mediators (SPMs) induce resolution of inflammation. SPMs are
derivatives of n-3 and n-6 PUFAs and may mediate their beneficial effects. It is unknown
whether supplementation with PUFAs influences the production of SPMs. Alzheimer's
disease (AD) is associated with brain inflammation and reduced levels of SPMs. The
OmegAD study is a randomized, double-blind, and placebo-controlled clinical trial on AD
patients, in which placebo or a supplement of 1.7 g DHA and 0.6 g EPA was taken daily for 6 …
derivatives of n-3 and n-6 PUFAs and may mediate their beneficial effects. It is unknown
whether supplementation with PUFAs influences the production of SPMs. Alzheimer's
disease (AD) is associated with brain inflammation and reduced levels of SPMs. The
OmegAD study is a randomized, double-blind, and placebo-controlled clinical trial on AD
patients, in which placebo or a supplement of 1.7 g DHA and 0.6 g EPA was taken daily for 6 …
