Objective There is increasing awareness of neuronal autoantibodies and their impact on the
pathogenesis of epilepsy. We investigated children with focal epilepsy in order to provide an
estimate of autoantibody frequency within a pediatric population without prima facie
evidence of encephalitis using a broad panel of autoantibodies. This was done to assess the
specificity of antibodies and to see whether antibodies might be of modifying influence on
the course of focal epilepsies. Method We searched for autoantibodies in 124 patients with …