A large series of clinical and experimental studies supports a link between inflammation and
epilepsy, indicating that inflammatory processes within the brain are important contributors
to seizure recurrence and precipitation. Systemic inflammation can precipitate seizures in
children suffering from epileptic encephalopathies, and hallmarks of a chronic inflammatory
state have been found in patients with temporal lobe epilepsy. Research performed on
animal models of epilepsy further corroborates the idea that seizures upregulate …