Bilateral deep brain stimulation vs best medical therapy for patients with advanced Parkinson disease: a randomized controlled trial

FM Weaver, K Follett, M Stern, K Hur, C Harris… - Jama, 2009 - jamanetwork.com
Context Deep brain stimulation is an accepted treatment for advanced Parkinson disease
(PD), although there are few randomized trials comparing treatments, and most studies
exclude older patients. Objective To compare 6-month outcomes for patients with PD who
received deep brain stimulation or best medical therapy. Design, Setting, and Patients
Randomized controlled trial of patients who received either deep brain stimulation or best
medical therapy, stratified by study site and patient age (< 70 years vs≥ 70 years) at 7 …