Efficacy and safety of deep brain stimulation in Tourette syndrome: the international Tourette syndrome deep brain stimulation public database and registry

D Martinez-Ramirez, J Jimenez-Shahed… - JAMA …, 2018 - jamanetwork.com
Importance Collective evidence has strongly suggested that deep brain stimulation (DBS) is
a promising therapy for Tourette syndrome. Objective To assess the efficacy and safety of
DBS in a multinational cohort of patients with Tourette syndrome. Design, Setting, and
Participants The prospective International Deep Brain Stimulation Database and Registry
included 185 patients with medically refractory Tourette syndrome who underwent DBS
implantation from January 1, 2012, to December 31, 2016, at 31 institutions in 10 countries …