Numerous murine models have been developed to study human cancers and advance the
understanding of cancer treatment and development. Here, a preclinical, murine pancreatic
tumor model of hepatic metastases via a hemispleen injection of syngeneic murine
pancreatic tumor cells is described. This model mimics many of the clinical conditions in
patients with metastatic disease to the liver. Mice consistently develop metastases in the
liver allowing for investigation of the metastatic process, experimental therapy testing, and …