Vitronectin and its receptors
B Felding-Habermann, DA Cheresh - Current opinion in cell biology, 1993 - Elsevier
B Felding-Habermann, DA Cheresh
Current opinion in cell biology, 1993•ElsevierThe extracellular matrix protein vitronectin is recognized as an adhesive substrate by cells
expressing at least one of four known vitronectin receptors: integrins αvβ1, αvβ3, αvβ5 or
αIIbβ3. Cell interaction with vitronectin may induced spreading and migration and have an
effect on cell growth and differentiation in specific processes, such as tumor growth and
metastasis, wound healing, bone resorption and viral infection.
expressing at least one of four known vitronectin receptors: integrins αvβ1, αvβ3, αvβ5 or
αIIbβ3. Cell interaction with vitronectin may induced spreading and migration and have an
effect on cell growth and differentiation in specific processes, such as tumor growth and
metastasis, wound healing, bone resorption and viral infection.
Abstract
The extracellular matrix protein vitronectin is recognized as an adhesive substrate by cells expressing at least one of four known vitronectin receptors: integrins αvβ1, αvβ3, αvβ5 or αIIbβ3. Cell interaction with vitronectin may induced spreading and migration and have an effect on cell growth and differentiation in specific processes, such as tumor growth and metastasis, wound healing, bone resorption and viral infection.
Elsevier