1812 Journal of Lipid Research Volume 55, 2014 concentrations in body fluids and
atherosclerotic tissues (23). Its amphipathic nature and detergent-like properties can induce
nonspecific cellular responses. In physiological settings, these effects are in large part
prevented because lysoPC forms complexes with serum proteins, immunoglobulins, and
plasma membranes. Thus, total lysoPAF/lysoPC concentrations do not relate to
bioavailability and it is highly unlikely that the relatively small amounts of free …