SARS-CoV-2 placentitis and intraparenchymal thrombohematomas among COVID-19 infections in pregnancy
A Huynh, JK Sehn, IT Goldfarb, J Watkins… - JAMA network …, 2022 - jamanetwork.com
Systematic meta-analysis did not find increased stillbirth risk during the early months of the
SARS-CoV-2 pandemic, 1 but increased rates have been reported during the Delta wave. 2,
3 Pathology literature has documented diagnostic histopathologic features of SARS-CoV-2
placental infection: syncytiotrophoblast necrosis, increased perivillous fibrin, and
intervillositis, with trophoblast infection confirmed by SARS-CoV-2 RNA in situ hybridization
(RNA-ISH) or immunohistochemistry. 4 SARS-CoV-2 placentitis causes severe placental …
SARS-CoV-2 pandemic, 1 but increased rates have been reported during the Delta wave. 2,
3 Pathology literature has documented diagnostic histopathologic features of SARS-CoV-2
placental infection: syncytiotrophoblast necrosis, increased perivillous fibrin, and
intervillositis, with trophoblast infection confirmed by SARS-CoV-2 RNA in situ hybridization
(RNA-ISH) or immunohistochemistry. 4 SARS-CoV-2 placentitis causes severe placental …