The lymphatic vasculature revisited—new developments in the zebrafish

Y Padberg, S Schulte-Merker, A Van Impel - Methods in cell biology, 2017 - Elsevier
The lymphatic system is lined by endothelial cells and part of the vasculature. It is essential
for tissue fluid homeostasis, absorption of dietary fats, and immune surveillance in
vertebrates. Misregulation of lymphatic vessel formation and dysfunction of the lymphatic
system have been indicated in a number of pathological conditions including lymphedema
formation, obesity or chronic inflammatory diseases such as rheumatoid arthritis. In
zebrafish, lymphatics were discovered about 10 years ago, and the underlying molecular …