von-Hippel Lindau and hypoxia-inducible factor at the center of renal cell carcinoma biology
NH Shirole, WG Kaelin - Hematology/Oncology Clinics, 2023 - hemonc.theclinics.com
Kidney cancer is one of the 10 most common cancers in the developed world and is
increasing in incidence. In 2020 there were more than 400,000 new cases of kidney cancer
and almost 179,368 deaths from this disease worldwide. 1 In the United States it is
estimated that there will be 81,800 new cases of kidney cancer and 14,890 deaths in 2023.
2 Risk factors for kidney cancer include older age, tobacco use, obesity, hypertension,
certain chronic kidney diseases, certain industrial exposures, and a positive family history of …
increasing in incidence. In 2020 there were more than 400,000 new cases of kidney cancer
and almost 179,368 deaths from this disease worldwide. 1 In the United States it is
estimated that there will be 81,800 new cases of kidney cancer and 14,890 deaths in 2023.
2 Risk factors for kidney cancer include older age, tobacco use, obesity, hypertension,
certain chronic kidney diseases, certain industrial exposures, and a positive family history of …
