[HTML][HTML] High frequency of GNA14, GNAQ, and GNA11 mutations in cherry hemangioma: a histopathological and molecular study of 85 cases indicating GNA14 as the …

JY Liau, JC Lee, JH Tsai, CC Chen, YC Chung… - Modern Pathology, 2019 - Elsevier
Cherry hemangioma is the most common hemangioma in adult life. Neoplastic and non-
neoplastic theories had both been proposed for its pathogenesis, but its nature is still poorly
understood. We noted a significant subset of anastomosing hemangiomas and congenital
hemangiomas harbored a population of small capillaries surrounded by a perivascular
hyaline layer, reminiscent of the vessels seen in cherry hemangioma. Both anastomosing
hemangioma and congenital hemangioma harbor recurrent mutations in exon 5 of GNAQ …