Synergistic effect of estrogen and VEGF on the proliferation of hemangioma vascular endothelial cells
X Xiao, J Liu, M Sheng - Journal of pediatric surgery, 2004 - Elsevier
PURPOSE: The aim of this study was to observe the influences of estradiol (E2), vascular
endothelial growth factor (VEGF), and 4OH-tamoxifen (TAM) on the proliferation of
hemangioma vascular endothelial cells (HVECs). METHODS: Two strawberry hemangiomas
with positive estrogen receptor staining from 2 infants (cases 1 & 2) were used for HVECs
culture. The HVECs of passage 3 were cultured in estrogen-free improved minimum
essential medium and divided into 5 groups based on different treatments: group 1, no …
endothelial growth factor (VEGF), and 4OH-tamoxifen (TAM) on the proliferation of
hemangioma vascular endothelial cells (HVECs). METHODS: Two strawberry hemangiomas
with positive estrogen receptor staining from 2 infants (cases 1 & 2) were used for HVECs
culture. The HVECs of passage 3 were cultured in estrogen-free improved minimum
essential medium and divided into 5 groups based on different treatments: group 1, no …
